Research Progress in Pharmacology of Xiaoyaowan / 中国实验方剂学杂志

In traditional Chinese medicine， it is believed that the spleen is the foundation of acquired nature and the source of Qi and blood. All life activities of a person since birth depend on the water and grain essence transported by spleen and stomach. The liver helps the spleen to strengthen the movement， the liver and spleen cooperate with each other. The liver and the spleen are invigorated， so that the Qi and blood are sufficient. The external energy can nourish the limbs， muscles and fur. The Qi and blood can be supplied to the internal organs， meridians and bones， and the body can be nourished both inside and outside to strengthen the acquired foundation. Emotional dissatisfaction can lead to stagnation of liver Qi， loss of spleen Qi， failure to dredge Qi， and deficiency of spleen Qi， forming the syndrome of liver depression and spleen deficiency. Its clinical manifestations include the symptoms of liver Qi stagnation such as depression， stamina， and chest fullness， as well as symptoms of spleen deficiency such as anorexia， abdominal distension， loose stools. Xiaoyaowan is an effective classic prescription for the treatment of liver stagnation and spleen deficiency syndrome， which is based on the dosage form of Xiaoyaosan in Prescriptions of the Bureau of Taiping People's Welfare Pharmacy. It has the effect of relieving depression， nourishing blood and invigorating spleen. In modern research， it has been found that Xiaoyaowan has good curative effect in the treatment of endocrine diseases， liver diseases， immune diseases， and neurological diseases， etc. It was praised by the famous medical scientist YE Tian-shi in the Qing Dynasty as "the holy medicine for women"， with a wide range of significant curative effects gynecology. Progress has been also made in pharmacological research. In this article， we have searched and consulted the relevant literature reports of Xiaoyaowan in recent years， summarized the key directions of the pharmacological research literature， and proposed deficiencies to provide relevant basis for the in-depth study of Xiaoyao pill in the future.

Periarthritis of shoulder treated with deep puncture by elongated needle combined with spike-hooked needle and cupping: a multicentral randomized controlled study / 中国针灸

<p><b>OBJECTIVE</b>To assess the clinical efficacy and the safety for periarthritis of shoulder treated with deep puncture by elongated needle combined with spike-hooked needle and cupping.</p><p><b>METHODS</b>A multicentral randomized controlled study was adopted. One hundred and twenty cases were divided into an observation group and a control group, 60 cases in each one. In observation group, elongated needle, spike-hooked needle and cupping were used to stimulate Jianyu (LI 15), Naoshu (SI 10), Naohui (TE 13) and Jianqian (Extra). In control group, a conventional needling and cupping were applied to the same points as observation group. Visual Analogue Scale (VAS) and Melle evaluation for the function activity of shoulder joint were adopted to assess and compare the efficacy on analgesia and the effect on shoulder joint range of motion before and after treatment in two groups.</p><p><b>RESULTS</b>In observation group, the cured and markedly effective rate of analgesia was 91.7% (55/60), which was obviously better than 20.4% (12/59) in control group (P < 0.001). Concerning to the improvements of the range of motion in shoulder joint, the cured and markedly effective rate in observation group was 91.7% (55/60), which was better than 18. 6% (11/59) in control group (P < 0.001). VAS score and Melle score after treatment were apparently improved as compared with those before treatment in two groups (all P < 0.001). The improvements in observation group were superior to those in control group (both P < 0.001). There was no adverse event reported during the treatment in two groups.</p><p><b>CONCLUSION</b>The deep puncture by elongated needle combined with spike-hooked needle and cupping achieves a significant clinical efficacy on periarthritis of shoulder and has no adverse reaction reported.</p>

Control study on acupuncture and medication for treatment of primary simple premature ejaculation / 中国针灸

<p><b>OBJECTIVE</b>To compare therapeutic effects of acupuncture and medication on primary simple premature ejaculation.</p><p><b>METHODS</b>One hundred and eleven cases were randomly divided into an acupuncture group (n = 56) and a medication group (n = 55). The acupuncture group was treated by acupuncture with acupoint group I Xinshu (BL 15), Ganshu (BL 18), Pishu (BL 20), Shenshu (BL 23) and acupoint group II Guanyuan (CV 4), Zhongji (CV 3), Sanyinjiao (SP 6), Taixi (KI 3), Taichong (LR 3) alternately selected, one acupoint group daily. The medication group was treated with oral administration of Sailete tablets, 20 mg each tablet, one tablet each night. After they were treated for one course, their therapeutic effects were compared.</p><p><b>RESULTS</b>The total effective rate was 82.1% in the acupuncture group and 63.6% in the medication group; the cumulative score after treatment was 12.56 +/- 3.84 in the acupuncture group and 11.50 +/- 3.77 in the medication group, with a significant difference between the two groups in the therapeutic effect (P < 0.05).</p><p><b>CONCLUSION</b>Acupuncture has a better therapeutic effect on primary simple premature ejaculation.</p>

Observation on therapeutic effect of warm needle moxibustion on chronic non-bacterial prostatitis / 中国针灸

<p><b>OBJECTIVE</b>To observe the therapeutic effect of warm needle moxibustion on chronic non-bacterial prostatitis.</p><p><b>METHODS</b>One hundred and twenty-five cases were randomly divided into a warm needle moxibustion group (n = 42), an acupuncture group (n = 41) and a western medicine group (n = 42). The warm needle moxibustion group was treated with acupuncture at Shenshu (BL 23), Ganshu (BL 18), Zhibian (BL 54) with no retention of the needles, and warm needle moxibustion on Guanyuan (CV 4), Zhongji (CV 3), Yinlingquan (SP 9), Sanyin-jiao (SP 6), once daily; the acupuncture group with acupuncture at the same acupoints as the warm needle moxibus tion group with no moxibustion; and the western medicine group with oral administration of Prostat Tablets, one tablet each time, twice daily. The therapeutic effects and scores of chronic prostatitis symptom indexes (NIH-CPSI) were compared.</p><p><b>RESULTS</b>The total effective rate was 88.10% in the warm needle moxibustion group, 63.41% in the acupuncture group and 66.67% in the western medicine group, the warm needle moxibustion group being better than the acupuncture group and the western medicine group (both P < 0.05). After treatment, the scores of NIH-CPSI was 11.92 +/- 7.11 in the warm needle moxibustion group, 16.08 +/- 6.83 in the acupuncture group and 15.66 +/- 5.88 in the western medicine group, with significant decreases in the 3 groups as compared with those before treatment (all P < 0.01), and after treatment, the score in the warm needle moxibustion group was significant different to that of the acupuncture group or the western medicine group (both P < 0.01).</p><p><b>CONCLUSION</b>The warm needle moxibustion has a good therapeutic effect on chronic non-bacterial prostatitis.</p>

Clinical observation on acupuncture combined with diet control for treatment of simple obesity / 中国针灸

<p><b>OBJECTIVE</b>To search for an effective method for increasing the therapeutic effect on simple obesity.</p><p><b>METHODS</b>Three hundred and thirty-four cases of simple obesity were randomly divided into an observation group (n=112), a control group I (n=112) and a control group II (n=110). The observation group was treated with acupuncture at Zhongwan (CV 12), Tianshu (ST 25), Guanyuan (CV 4), and diet control, the control group I with simple acupuncture and the control group II with diet control.</p><p><b>RESULTS</b>Of the 334 cases enrolled, 66 withdrawn from the experiment (3 cases in the observation group, 5 cases in the control group I and 58 cases in the control group II ). The total effective rate was 91.8% in the observation group, 75.7% in the control group I and 73.1% in the control group I, with a significant differences as the observation group compared with the control group I or the control group II (both P<0.005); the effect-rebounding rate one year later in the observation group or the control group I was significantly different from that of the control group II (both P<0.001); and the number of cases withdrawning from the experiment in the control group II was significantly different from that in the observation group or in the control group I (both P<0.001).</p><p><b>CONCLUSION</b>Acupuncture combined with diet control has a significant effect on simple obesity with a lower rate of the effect-rebounding, and it is easily accepted.</p>

Clinical observation on acupuncture for treatment of allergic rhinitis / 中国针灸

<p><b>OBJECTIVE</b>To find out an effective acupuncture and moxibustion therapy for allergic rhinitis.</p><p><b>METHODS</b>One hundred and thirty-five cases were randomly divided into a treatment group, a control group I , and a control group II , 45 cases in each group. The treatment group were treated with acupuncture at Yingxiang (LI 20), Shangyingxiang (EX-HN 8), Yintang (EX-HN 3), Hegu (LI 4), Fengchi (GB 20), Dazhui (GV 14), Feishu (BL 13); the control group I with Yingxiang (LI 20), Shangyingxiang (EX-HN 8), Yintang (EX-HN 3), Hegu (LI 4), and the control group II with oral administration of Biyankang tablets, 4 tablets each time, thrice each day. Acupuncture was given one session daily, 10 sessions constituting one course. Their therapeutic effects were compared after treatment of 2 courses and were followed up a half year later.</p><p><b>RESULTS</b>The total effective rate was 91.1% in the treatment group, 71.1% in the control group I and 46.7% in the control group II, with a significant difference among the 3 groups (P<0.05), and with a significant difference in the recurrence rate one year later among the cured cases of the 3 groups (P<0.05).</p><p><b>CONCLUSION</b>Acupuncture has a definite therapeutic effect on allergic rhinitis, with a better result by acupuncture with the anterior and posterior acupoint association method.</p>